Boc-L-pyroglutamic acid methyl ester
Boc-L-Pyroglutamic acid methyl ester
CAS: 108963-96-8
Molecular Formula: C11H17NO5
Boc-L-pyroglutamic acid methyl ester - Names and Identifiers
| Name | Boc-L-Pyroglutamic acid methyl ester |
| Synonyms | BOC-PYR-OME Methyl Boc-L-Pyroglutamate Methyl Boc-L-Pyroglutamate (S)-METHYL-N-BOC-PYROGLUTAMATE Boc-L-Pyroglutamic acid methyl ester BOC-L-PYROGLUTAMIC ACID METHYL ESTER (S)-N-BOC-5-METHOXYCARBONYL-2-PYRROLIDINONE N-tert-Butoxycarbonyl-L-pyroglutamic acid methyl ester 1-tert-butyl 2-methyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate 1,2-Pyrrolidinecarboxylic acid 5-oxo,1-(tertButyl)-2-methylester (S)-N-(tert-Butoxycarbonyl)-2-pyrrolidinone-5-carboxylic acid methyl |
| CAS | 108963-96-8 |
| EINECS | 600-890-6 |
| InChI | InChI=1/C11H17NO5/c1-11(2,3)17-10(15)12-7(9(14)16-4)5-6-8(12)13/h7H,5-6H2,1-4H3/t7-/m0/s1 |
Boc-L-pyroglutamic acid methyl ester - Physico-chemical Properties
| Molecular Formula | C11H17NO5 |
| Molar Mass | 243.26 |
| Density | 1.209±0.06 g/cm3(Predicted) |
| Melting Point | 68-72 °C69-74 °C |
| Boling Point | 361.6±35.0 °C(Predicted) |
| Flash Point | 172.5°C |
| Solubility | Soluble in dichloromethane. |
| Vapor Presure | 2.04E-05mmHg at 25°C |
| Appearance | White crystal |
| Color | White to Almost white |
| pKa | -4.28±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Easy to absorb moisture, `sensitive` to heat and light |
| Refractive Index | 1.487 |
| MDL | MFCD06809720 |
Boc-L-pyroglutamic acid methyl ester - Risk and Safety
| Risk Codes | R36 - Irritating to the eyes R43 - May cause sensitization by skin contact R50 - Very Toxic to aquatic organisms |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| HS Code | 29337900 |
| Hazard Class | 9 |
Boc-L-pyroglutamic acid methyl ester - Introduction
Boc-L-pyroglutamic acid methyl ester is an organic compound whose chemical formula is C12H19NO5. This compound is commonly used as an intermediate in organic synthesis.
Boc-L-pyroglutamic acid methyl ester is a white or off-white solid, soluble in ethanol and dimethylformamide. It has the structure of a standard amino acid with a Boc protecting group on the β-amino acid, which can be removed in organic synthesis reactions.
Boc-L-pyroglutamic acid methyl ester is often used as a protecting group in organic synthesis to keep it stable during the synthesis, and then the protecting group is removed by chemical reaction. It can also be used to synthesize other biologically active complex organic compounds, such as drugs and peptides.
The method for preparing Boc-L-pyroglutamic acid methyl ester includes reacting pyroglutamic acid and methyl ester, and introducing a protecting group under appropriate conditions. This method of synthesis is common in the laboratory.
Regarding safety information, Boc-L-pyroglutamate methyl ester is generally a low-toxicity compound. However, it is still necessary to observe laboratory safety regulations and correct protective measures, such as wearing appropriate protective gloves and glasses, and to operate in a well-ventilated environment. In addition, any chemicals used should be handled and stored appropriately to ensure safety and avoid accidents.
Boc-L-pyroglutamic acid methyl ester is a white or off-white solid, soluble in ethanol and dimethylformamide. It has the structure of a standard amino acid with a Boc protecting group on the β-amino acid, which can be removed in organic synthesis reactions.
Boc-L-pyroglutamic acid methyl ester is often used as a protecting group in organic synthesis to keep it stable during the synthesis, and then the protecting group is removed by chemical reaction. It can also be used to synthesize other biologically active complex organic compounds, such as drugs and peptides.
The method for preparing Boc-L-pyroglutamic acid methyl ester includes reacting pyroglutamic acid and methyl ester, and introducing a protecting group under appropriate conditions. This method of synthesis is common in the laboratory.
Regarding safety information, Boc-L-pyroglutamate methyl ester is generally a low-toxicity compound. However, it is still necessary to observe laboratory safety regulations and correct protective measures, such as wearing appropriate protective gloves and glasses, and to operate in a well-ventilated environment. In addition, any chemicals used should be handled and stored appropriately to ensure safety and avoid accidents.
Last Update：2024-04-09 20:52:54
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View History
Boc-L-pyroglutamic acid methyl ester
4-氨基-3-(2,6-二甲基苯基)-2-硫代-噻唑-5-甲酸乙酯
2-羟基-4-苯基嘧啶-5-羧酸乙酯
7-苯并呋喃甲酰胺, 4-氨基-5-氯-2,3-二氢-N-[1-(3-甲氧基丙基)-4-哌啶基]-
Ganoderma lucidum reference material
2 -(2 -(4-甲氧基苯基)乙炔基)苯甲醛
顺-13-二十二烯-1-醇
8-羟基-5-甲基-6-氧代-5,6-二氢-4H-苯并[F]咪唑并[1,5-A][1,4]二氮杂卓-3-羧酸乙酯
7-(1-乙基-5-甲基-吡唑-4-基)吡唑[1,5-A]嘧啶-2-羧酸
2-氧杂-8-氮杂螺[4.5]癸-4-醇
4-氨基-3-(2,6-二甲基苯基)-2-硫代-噻唑-5-甲酸乙酯
2-羟基-4-苯基嘧啶-5-羧酸乙酯
7-苯并呋喃甲酰胺, 4-氨基-5-氯-2,3-二氢-N-[1-(3-甲氧基丙基)-4-哌啶基]-
Ganoderma lucidum reference material
2 -(2 -(4-甲氧基苯基)乙炔基)苯甲醛
顺-13-二十二烯-1-醇
8-羟基-5-甲基-6-氧代-5,6-二氢-4H-苯并[F]咪唑并[1,5-A][1,4]二氮杂卓-3-羧酸乙酯
7-(1-乙基-5-甲基-吡唑-4-基)吡唑[1,5-A]嘧啶-2-羧酸
2-氧杂-8-氮杂螺[4.5]癸-4-醇